Zu "GeneID 4193" wurden 119 Artikel gefunden!
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Anti-phospho-MDM2 (Ser166), clone 29M35
Artikelnummer: NSJ-RQ8702
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. Phosphorylated MDM2 is a post-translationally modified form of the MDM2 protein, an E3 ubiquitin ligase that regulates the stability and activity of the tumor suppressor p53. Phosphorylation of MDM2 at specific residues modulates its...
| Schlagworte: | Anti-phospho-MDM2, Anti-phospho-Oncoprotein Mdm2, Anti-phospho-Double minute 2 protein, Anti-phospho-p53-binding protein... |
| Anwendung: | WB, IF, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-MDM2
Artikelnummer: ATA-HPA069791.100
Rabbit Polyclonal MDM2 Antibody against Human MDM2 proto-oncogene. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000020184: 88%, ENSRNOG00000006304: 84%....
| Schlagworte: | Anti-Hdm2, Anti-MDM2, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2, Anti-E3... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
393,00 €
Mdm2 E3 Ligase TR-FRET Kit
Artikelnummer: SBB-KF0030-KI01
South Bay Bio's MDM2 TR-FRET Ubiquitin Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto GST-MDM2 in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous TR-FRET detection of ubiquitin chain formation onto...
| Schlagworte: | MDM2, Hdm2, EC=2.3.2.27, Oncoprotein Mdm2, Double minute 2 protein, p53-binding protein Mdm2, E3 ubiquitin-protein ligase... |
| Anwendung: | Enzyme assays |
| Spezies-Reaktivität: | human |
1.451,00 €
MDM2, GST-tag
Artikelnummer: BPS-100409
Recombinant human MDM2 (Mouse double minute 2 homolog), full length encompassing amino acids 2-498 (end). In this construct the N-terminal end of MDM2 is fused with GST. A short peptide linker placed between GST and the protein includes a PreScission Protease Cleavage Site to facilitate removal of the GST portion....
| Schlagworte: | Hdm2, MDM2, Oncoprotein Mdm2, Double minute 2 protein, p53-binding protein Mdm2, E3 ubiquitin-protein ligase Mdm2,... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 83 kD |
566,00 €
Anti-MDM2
Artikelnummer: ARG51392.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1....
| Schlagworte: | Anti-Hdm2, Anti-MDM2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 471,00 €
Anti-phospho-MDM2 (Ser166)
Artikelnummer: ARG51834.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1....
| Schlagworte: | Anti-phospho-Hdm2, Anti-phospho-MDM2, EC=6.3.2.-, Anti-phospho-Oncoprotein Mdm2, Anti-phospho-Double minute 2 protein,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 471,00 €
Anti-MDM2 (isoform), Internal
Artikelnummer: ARG63943.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1....
| Schlagworte: | Anti-MDM2, Anti-Hdm2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-MDM2
Artikelnummer: ARG65770.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1....
| Schlagworte: | Anti-Hdm2, Anti-MDM2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, monkey, mouse |
ab 460,00 €
Anti-MDM2
Artikelnummer: NSJ-R30449
0.5mg/ml if reconstituted with 0.2ml sterile DI water. MDM2 is an important negative regulator of the p53 tumor suppressor. The protein functions both as an E3 ubiquity lipase that recognizes the N-terminal trans-activation domain(TAD) of the p53 tumor suppressor and an inhibitor of p53 transcriptional activation....
| Schlagworte: | Anti-MDM2, Anti-Hdm2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-MDM2
Artikelnummer: NSJ-R33423-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Mouse double minute 2 Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and...
| Schlagworte: | Anti-MDM2, Anti-Hdm2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-MDM2
Artikelnummer: E-AB-31995.120
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety...
| Schlagworte: | Anti-Hdm2, Anti-MDM2, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2, Anti-E3... |
| Anwendung: | WB, IHC (paraffin), IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, monkey |
ab 89,00 €
Anti-MDM2, clone MDM2/2414
Artikelnummer: NSJ-V7305-100UG
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result...
| Schlagworte: | Anti-MDM2, Anti-Hdm2, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2, Anti-E3... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 375,00 €