Zu "GeneID 4193" wurden 128 Artikel gefunden!
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NEU
Anti-MDM2
Artikelnummer: NSJ-F42269-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. MDM2 is a target of the transcription factor tumor protein p53. This protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of MDM2 can result in excessive...
| Schlagworte: | Anti-MDM2, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2, Anti-E3 ubiquitin-protein... |
| Anwendung: | IHC, IF, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
NEU
Anti-MDM2 (pT218)
Artikelnummer: NSJ-F48546-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. MDM2 is a target of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of MDM2 can result in excessive...
| Schlagworte: | Anti-MDM2, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2, Anti-E3 ubiquitin-protein... |
| Anwendung: | DB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
NEU
Anti-MDM2 (pS395)
Artikelnummer: NSJ-F48579-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. MDM2 is a target of the transcription factor tumor protein p53. This protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of MDM2 can result in excessive...
| Schlagworte: | Anti-MDM2, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2, Anti-E3 ubiquitin-protein... |
| Anwendung: | DB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-phospho-MDM2 (Ser166), clone 29M35
Artikelnummer: NSJ-RQ8702
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. Phosphorylated MDM2 is a post-translationally modified form of the MDM2 protein, an E3 ubiquitin ligase that regulates the stability and activity of the tumor suppressor p53. Phosphorylation of MDM2 at specific residues modulates its...
| Schlagworte: | Anti-phospho-MDM2, Anti-phospho-Oncoprotein Mdm2, Anti-phospho-Double minute 2 protein, Anti-phospho-p53-binding protein... |
| Anwendung: | WB, IF, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-MDM2
Artikelnummer: ATA-HPA069791.100
Rabbit Polyclonal MDM2 Antibody against Human MDM2 proto-oncogene. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000020184: 88%, ENSRNOG00000006304: 84%....
| Schlagworte: | Anti-Hdm2, Anti-MDM2, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2, Anti-E3... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
393,00 €
Mdm2 E3 Ligase TR-FRET Kit
Artikelnummer: SBB-KF0030-KI01
South Bay Bio's MDM2 TR-FRET Ubiquitin Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto GST-MDM2 in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous TR-FRET detection of ubiquitin chain formation onto...
| Schlagworte: | MDM2, Hdm2, EC=2.3.2.27, Oncoprotein Mdm2, Double minute 2 protein, p53-binding protein Mdm2, E3 ubiquitin-protein ligase... |
| Anwendung: | Enzyme assays |
| Spezies-Reaktivität: | human |
1.451,00 €
MDM2, GST-tag
Artikelnummer: BPS-100409
Recombinant human MDM2 (Mouse double minute 2 homolog), full length encompassing amino acids 2-498 (end). In this construct the N-terminal end of MDM2 is fused with GST. A short peptide linker placed between GST and the protein includes a PreScission Protease Cleavage Site to facilitate removal of the GST portion....
| Schlagworte: | Hdm2, MDM2, Oncoprotein Mdm2, Double minute 2 protein, p53-binding protein Mdm2, E3 ubiquitin-protein ligase Mdm2,... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 83 kD |
566,00 €
Anti-MDM2
Artikelnummer: ARG51392.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1....
| Schlagworte: | Anti-Hdm2, Anti-MDM2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 471,00 €
Anti-phospho-MDM2 (Ser166)
Artikelnummer: ARG51834.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1....
| Schlagworte: | Anti-phospho-Hdm2, Anti-phospho-MDM2, EC=6.3.2.-, Anti-phospho-Oncoprotein Mdm2, Anti-phospho-Double minute 2 protein,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 471,00 €
Anti-MDM2 (isoform), Internal
Artikelnummer: ARG63943.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1....
| Schlagworte: | Anti-MDM2, Anti-Hdm2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-MDM2
Artikelnummer: ARG65770.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1....
| Schlagworte: | Anti-Hdm2, Anti-MDM2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, monkey, mouse |
ab 460,00 €
Anti-MDM2
Artikelnummer: NSJ-R30449
0.5mg/ml if reconstituted with 0.2ml sterile DI water. MDM2 is an important negative regulator of the p53 tumor suppressor. The protein functions both as an E3 ubiquity lipase that recognizes the N-terminal trans-activation domain(TAD) of the p53 tumor suppressor and an inhibitor of p53 transcriptional activation....
| Schlagworte: | Anti-MDM2, Anti-Hdm2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €