Zu "GeneID 23385" wurden 18 Artikel gefunden!

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Anti-Nicastrin
Anti-Nicastrin

Artikelnummer: A304-464A

Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335). The gamma-...
Schlagworte: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-Nicastrin
Anti-Nicastrin

Artikelnummer: 600-401-DB1

Anti-Nicastrin Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Nicastrin from other sources has not been determined. Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage...
Schlagworte: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin
Anwendung: ELISA, IHC, IFM, WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
684,00 €
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Anti-Nicastrin
Anti-Nicastrin

Artikelnummer: 600-401-DB2

Anti-Nicastrin Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Nicastrin from other sources has not been determined. Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage...
Schlagworte: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin
Anwendung: ELISA, IHC, IFM, WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
684,00 €
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Anti-Nicastrin
Anti-Nicastrin

Artikelnummer: NSJ-R31374

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Nicastrin, also known as NCSTN, is aproteinthat is a part of the gamma secretase protein complex. It is mapped to 1q23.2. This gene is not catalytically active, but instead promotes the maturation and proper trafficking of the other proteins in the gamma...
Schlagworte: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin, Nicastrin Antibody
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
755,00 €
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Anti-NCSTN
Anti-NCSTN

Artikelnummer: E-AB-11441.120

This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex...
Schlagworte: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin, NCSTN Polyclonal Antibody
Anwendung: WB, IHC, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 71,00 €
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Anti-NCSTN
Anti-NCSTN

Artikelnummer: E-AB-15254.120

This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex...
Schlagworte: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin, NCSTN Polyclonal Antibody
Anwendung: IHC, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 71,00 €
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Anti-NCSTN / Nicastrin
Anti-NCSTN / Nicastrin

Artikelnummer: ARG40091.100

Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335, PubMed:30598546,...
Schlagworte: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: mouse, rat
624,00 €
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Anti-NCSTN
Anti-NCSTN

Artikelnummer: ATA-HPA054846.100

Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335, PubMed:30598546,...
Schlagworte: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 300,00 €
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Anti-NCSTN
Anti-NCSTN

Artikelnummer: ATA-HPA070642.100

Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335, PubMed:30598546,...
Schlagworte: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin
Anwendung: ICC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 300,00 €
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Nicastrin / NCSTN Protein (His tag) (recombinant human)
Nicastrin / NCSTN Protein (His tag) (recombinant human)

Artikelnummer: E-PKSH031225.50

Protein Construction: A DNA sequence encoding the human NCSTN (NP_056146.1) extracellular domain (Met 1-Glu 669) was expressed, with a polyhistidine tag at the C-terminus. Sequence: Met 1-Glu 669. Fusion tag: C-His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 110-120 kDa....
Schlagworte: NCSTN, KIAA0253, Nicastrin, Recombinant Human Nicastrin / NCSTN Protein (His tag)
Exprimiert in: Human cells
Ursprungsart: human
MW: 72.4 kD
1.025,00 €
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NCSTN, Human nicastrin, Real Time PCR Primer Set
NCSTN, Human nicastrin, Real Time PCR Primer Set

Artikelnummer: VHPS-6091

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: NCSTN, KIAA0253, Nicastrin
Anwendung: RNA quantification
43,00 €
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Anti-Nicastrin (NCSTN, APH2, KIAA0253, RP11-517F10.1, UNQ1874/PRO4317)
Anti-Nicastrin (NCSTN, APH2, KIAA0253, RP11-517F10.1,...

Artikelnummer: N2525-08A.100

Nicastrin is a transmembrane glycoprotein serving as an essential component of the gamma-secretase complex (1,2). Nicastrin protein is physically associated with presenilin and plays an important role in stabilization and correct localization of presenilin to the membrane-bound y-secretase complex (3). Nicastrin...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: hamster, human, monkey, mouse, rat
ab 439,00 €
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