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BI605906
Artikelnummer: TGM-T14567-100mg
Description: BI605906 is an IKKbeta inhibitor that inhibits tumor necrosis factor alpha-dependent IkappaB degradation and expression of the pro-inflammatory mediator interleukin-6, which can be used to study inflammatory skin diseases such as psoriasis. Target: IkappaB/IKK, IL Receptor. Smiles:...
| Schlagworte: | BI 605906, BI-605906 |
| Anwendung: | IKK beta inhibitor |
| CAS | 960293-88-3 |
| MW: | 432.51 D |
ab 31,00 €
BI-605906
Artikelnummer: Cay19184-1
BI-605906 is an inhibitor of inhibitor of kappa B kinase subunit beta (IKKbeta, IC50 = 380 nM). It is selective for IKKbeta over insulin-like growth factor 1 (IGF1, IC50 = 7.6 µM) and over 100 kinases in a panel up to 10 µM. BI-605906 partially inhibits IL-1-stimulated activation of IKKepsilon/TBK1 in vitro....
| Schlagworte: | 3-amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]-thieno[2,3-b]pyridine-2-carboxamide |
| Anwendung: | IKK beta inhibitor |
| CAS | 960293-88-3 |
| MW: | 432.5 D |
ab 104,00 €
