Zu "959850-74-9" wurden 2 Artikel gefunden!
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AP1189 (acetate)
Artikelnummer: Cay37400-1
AP1189 is a biased agonist of melanocortin receptor 1 (MC1R) and MC3R. It induces ERK1 and ERK2 phosphorylation but not canonical cAMP production in HEK293 cells expressing human MC1R or MC3R when used at concentrations ranging from 10 pM to 1 mM. AP1189 (0.1-10 nM) reduces zymosan-induced IL-1beta, IL-6, and...
| Schlagworte: | 2-[3-[1-(2-nitrophenyl)-1H-pyrrol-2-yl]-2-propen-1-ylidene]-hydrazinecarboximidamide, acetate |
| Anwendung: | Biased MC1R / MC3R agonist |
| CAS | 959850-74-9 |
| MW: | 358.4 D |
ab 60,00 €
AP1189 acetate
Artikelnummer: TGM-T9596-100mg
Description: AP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors. Target: Melanocortin Receptor. Smiles: O=[N+](C1=CC=CC=C1N2C(/C=C/C=N/NC(N)=N)=CC=C2)[O-].CC(O)=O. References: Montero-Melendez T, et al. Biased agonism as a novel strategy to harness the proresolving properties of...
| Anwendung: | Biased MC1R / MC3R agonist |
| CAS | 959850-74-9 |
| MW: | 358.35 D |
ab 39,00 €
