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Swinholide A
Artikelnummer: AG-CN2-0035-C050
Isolated from marine sponge Theonella swinhoei. Cell permeable dimeric dilactone macrolide - Cytotoxic compound - Specific actin filament (F-actin) inhibitor - Disrupts the actin cytoskeleton by sequestering actin dimers and rapidly severing actin filaments (F-actin) - Depolymerizes actin filaments (F-actin) -...
| Anwendung: | F-actin depolymerization |
| CAS | 95927-67-6 |
| MW: | 1389,9 D |
ab 108,00 €
Swinholide A
Artikelnummer: Cay19611-50
Swinholide A is a natural dimeric dilactone macrolide toxin that causes actin depolymerization in cells. It stabilizes actin dimers and also binds to and severs F-actin filaments. Swinholide A binds to G-actin in a 1:2 molar ratio and decreases the rate of nucleotide exchange in G-actin.Formal Name:...
| Schlagworte: | (1R,3S,5E,7E,11S,12S,13R,15S,16S,17S,19S,23R,25S,27E,29E,33S,34S,35R,37S,38S,39S,41S)-3,13,15,25,35,37-hexahydroxy-11,33-b... |
| Anwendung: | Actin depolymerization |
| CAS | 95927-67-6 |
| MW: | 1389.9 D |
ab 179,00 €
