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NS 11021
Artikelnummer: Cay15347-1
NS 11021 is an activator of large-conductance Ca2+-activated potassium channels (BKCa/KCa1.1). It is selective for BKCa and is thought to bind directly the alpha subunit. NS 11021 has been shown to relax intracavernous arterial rings and corpus cavernosum strips in vitro and to enhance erectile responses in intact...
| Schlagworte: | N'-[3,5-bis(trifluoromethyl)phenyl]-N-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-thiourea |
| Anwendung: | KCNMA1 activator |
| CAS | 956014-19-0 |
| MW: | 511.2 D |
ab 49,00 €
NS 11021
Artikelnummer: TGM-T4294-100mg
Description: NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels. Target: Potassium Channel. Smiles: FC(F)(F)c1cc(NC(=S)Nc2ccc(Br)cc2-c2nnn[nH]2)cc(c1)C(F)(F)F. References: Bentzen BH, et al. The small molecule NS11021 is a potent and specific activator of Ca2+-activated...
| Schlagworte: | NS11021 |
| Anwendung: | KCNMA1 activator |
| CAS | 956014-19-0 |
| MW: | 511.24 D |
ab 36,00 €
