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TTA-A2
TTA-A2

Artikelnummer: Cay42236-1

A T-type calcium channel inhibitor (IC50s = 89, 92, and 98 nM for Cav3.1, Cav3.2, and Cav3.3, respectively, in patch-clamp assays at -80 mV), selective for these channels over Cav1.2, Cav2.1, Cav2.2, and Cav2.3 in patch-clamp assays (IC50s = >30 µM for all at -90 mV), reduces the viability of spheroid A549 lung...
Schlagworte: 4-cyclopropyl-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)-2-pyridinyl]ethyl]-benzeneacetamide
Anwendung: T-type calcium channel inhibitor
CAS 953778-63-7
MW: 378.4 D
ab 93,00 €
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TTA-A2
TTA-A2

Artikelnummer: TGM-T8944-100mg

Description: TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels with IC50 values of 89 nM and 92 nM, respectively, at -80 and -100 mV holding...
CAS 953778-63-7
MW: 378.39 D
ab 100,00 €
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