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NEU
Timapiprant (sodium salt)
Artikelnummer: Cay42734-10
Timapiprant is a DP2 receptor antagonist (Ki = 0. µM). It is selective for DP2 over the additional prostanoid receptors DP1, TP, EP1-4, FP, and IP (Kis = >10 µM for all). Timapiprant inhibits calcium mobilization induced by prostaglandin D2 (PGD2, Cay-12010) in CHO cells expressing human DP2 (IC50 = 0. µM). It...
| Schlagworte: | OC000459, 5-fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indole-1-acetic acid, monosodium salt |
| Anwendung: | Prostaglandin D2 receptor (PTGDR) antagonist |
| CAS | 950688-14-9 |
| MW: | 370.36 D |
ab 68,00 €
Timapiprant sodium
Artikelnummer: TGM-T17099-1mL
Description: Timapiprant sodium inhibits mast cell activation of Th2 lymphocytes and eosinophils. Timapiprant sodium is a potent and selective D prostanoid receptor 2 antagonist. Timapiprant sodium potently displaces [3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), human native DP2...
| Schlagworte: | OC000459 sodium |
| CAS | 950688-14-9 |
| MW: | 371.367 D |
ab 31,00 €
