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Remodelin
Artikelnummer: Cay17346-1
Progeria is a genetic disorder that results in the appearance of premature aging. Genetically, progeria is characterized by a mutation in lamin A, which results in misshapen cell nuclei and DNA damage. Remodelin is a 2-thiazolylhydrazone derivative that, at 10 µM, improves nuclear architecture, chromatin...
| Schlagworte: | 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile |
| Anwendung: | NAT10 inhibitor |
| CAS | 949912-58-7 |
| MW: | 282.4 D |
ab 73,00 €
Remodelin
Artikelnummer: TGM-T3499-100mg
Description: Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10. Target: Histone Acetyltransferase. Smiles: Br.N#Cc1ccc(cc1)-c1csc(NN=C2CCCC2)n1. References: Larrieu D, et al. Chemical inhibition of NAT10 corrects defects of laminopathic cells. Science. 2014 May 2,344(6183):527-32.
| Anwendung: | NAT10 inhibitor |
| CAS | 949912-58-7 |
| MW: | 282.36 D |
ab 48,00 €
