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FPS-ZM1
Artikelnummer: TGM-T3259-100mg
Description: FPS-ZM1 is a high-affinity, RAGE-specific inhibitor that obstructs Abeta binding to the V domain of RAGE. Target: advanced glycation end products, Beta Amyloid. Smiles: Clc1ccc(cc1)C(=O)N(Cc1ccccc1)C1CCCCC1. References: Deane R, et al. J Clin Invest. 2012, 122(4):1377-1392.
| Anwendung: | RAGE antagonist |
| CAS | 945714-67-0 |
| MW: | 327.85 D |
ab 43,00 €
FPS-ZM1
Artikelnummer: Cay11909-10
FPS-ZM1 is a high-affinity inhibitor of the receptor for advanced glycation end products (RAGE, Ki = 25 nM). It blocks the binding of amyloid beta (Abeta) protein to RAGE and inhibits Abeta40- and Abeta42-induced cellular stress in RAGE-expressing cells. FPS-ZM1 is functional in mice when administered...
| Schlagworte: | 4-chloro-N-cyclohexyl-N-(phenylmethyl)-benzamide |
| Anwendung: | RAGE antagonist |
| CAS | 945714-67-0 |
| MW: | 327.9 D |
ab 41,00 €
