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AMG 900
Artikelnummer: TGM-T6380-100mg
Description: AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 values of 5 nM, 4 nM, and 1 nM, respectively. It exhibits over 10-fold selectivity for Aurora kinases compared to p38alpha, Tyk2, JNK2, Met, and Tie2. [Phase 1]. Target: p38 MAPK, Tyrosine Kinases, Aurora...
| Schlagworte: | AMG-900, AMG900 |
| Anwendung: | Aurora kinase inhibitor |
| CAS | 945595-80-2 |
| MW: | 503.58 D |
ab 45,00 €
AMG 900
Artikelnummer: Cay19176-1
Three Aurora kinases, A-C, are involved in phosphorylation events that are critical for the completion of mitosis. Their expression is elevated in a variety of human cancers. AMG 900 is an orally bioavailable, selective Aurora kinase inhibitor with IC50 values of 5, 4, and 1 nM for Aurora A, B, and C, respectively....
| Schlagworte: | N-[4-[[3-(2-amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine |
| Anwendung: | Aurora kinase inhibitor |
| CAS | 945595-80-2 |
| MW: | 503.6 D |
ab 61,00 €
