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CYM-5541
Artikelnummer: TGM-T3961-100mg
Description: CYM-5541 (ML249) is a selective and allosteric S1P3 receptor agonist. Target: S1P Receptor, LPL Receptor. Smiles: O=C(N(C1CCCCC1)C1CCCCC1)c1cc(on1)C1CC1. References: Jo E, et al. Novel selective allosteric and bitopic ligands for the S1P(3) receptor. ACS Chem Biol. 2012 Dec 21,7(12):1975-83.
| Schlagworte: | CID-17253208, ML249, CYM 5541 |
| Anwendung: | Allosteric agonist of S1P3 |
| CAS | 945128-26-7 |
| MW: | 316.44 D |
ab 33,00 €
CYM 5541
Artikelnummer: Cay15190-5
The sphingosine 1-phosphate (S1P) receptor S1P3 has roles in vasodilation, epithelial barrier function, cardioprotection, fibrosis, immunity, and inflammation. CYM 5541 is a selective, allosteric agonist of S1P3 (EC50 = 72-132 nM). It less effectively activates S1P1 (EC50 = 28-38 µM) and is ineffective at S1P2,...
| Schlagworte: | CID-17253208, ML-249, N,N-dicyclohexyl-5-cyclopropyl-3-isoxazolecarboxamide |
| Anwendung: | Allosteric agonist of S1P3 |
| CAS | 945128-26-7 |
| MW: | 316.4 D |
ab 85,00 €
