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QS11
Artikelnummer: Cay21247-10
QS11 is an inhibitor of GTPase activating protein of ADP-ribosylation factors (ARFGAPs) that increases activity of ARFs in NIH3T3 cells at a concentration of 1 µM. It activates Wnt/beta-catenin activity in a reporter assay using HEK293 cells (EC50 = 0.5 µM). QS11 exhibits synergy with Wnt-3a ligand-conditioned...
| Schlagworte: | betaS-[[9-([1,1'-biphenyl]-4-ylmethyl)-2-[(2,3-dihydro-1H-inden-5-yl)oxy]-9H-purin-6-yl]amino]-benzenepropanol |
| Anwendung: | Wnt Synergist, ARFGAP1 inhibitor |
| CAS | 944328-88-5 |
| MW: | 567.7 D |
ab 51,00 €
QS11
Artikelnummer: TGM-T4022-100mg
Description: QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/beta-catenin signaling pathway to upregulate beta-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells. Target:...
| Schlagworte: | QS 11 |
| Anwendung: | Wnt Synergist, ARFGAP1 inhibitor |
| CAS | 944328-88-5 |
| MW: | 567.68 D |
ab 30,00 €
