Zu "942918-07-2" wurden 3 Artikel gefunden!
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GSK1070916
Artikelnummer: Cay22953-1
GSK1070916 is a potent and ATP-competitive inhibitor of Aurora kinases B and C (Kis = 0.38 and 1.5 nM, respectively). It is >250-fold selective for Aurora B and C over Aurora A. GSK1070916 inhibits proliferation of A549 lung cancer cells in vitro (EC50 = 7 nM). It also inhibits proliferation in a panel of 100 tumor...
| Schlagworte: | N'-[4-[4-[2-[3-[(dimethylamino)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-ethyl-1H-pyrazol-3-yl]phenyl]-N,N-dimethyl-... |
| Anwendung: | Aurora B/C kinase inhibitor |
| CAS | 942918-07-2 |
| MW: | 507.6 D |
ab 60,00 €
GSK-1070916
Artikelnummer: LKT-G7444.1
AurKB/C inhibitor.
| Anwendung: | AurKB/C inhibitor |
| CAS | 942918-07-2 |
| MW: | 507.63 D |
ab 166,00 €
GSK-1070916
Artikelnummer: TGM-T6129-100mg
Description: GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1. Target: FLT, Apoptosis, Aurora Kinase, Tie-2, AMPK. Smiles:...
| Schlagworte: | GSK-1070916A, GSK1070916 |
| Anwendung: | Aurora B/C kinase inhibitor |
| CAS | 942918-07-2 |
| MW: | 507.63 D |
ab 39,00 €
