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JK-P3
Artikelnummer: TGM-T4425-100mg
Description: JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 µM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation. Target: VEGFR....
| Anwendung: | VEGFR2 inhibitor |
| CAS | 942655-44-9 |
| MW: | 323.35 D |
ab 34,00 €
JK-P3
Artikelnummer: Cay37555-10
JK-P3 is an inhibitor of the tyrosine kinases VEGFR2, FGFR1, and FGFR3 (IC50s = 7.83, 27, and 5.18 µM, respectively). It decreases VEGF-A-induced VEGFR2 phosphorylation in human umbilical vein endothelial cells (HUVECs) when used at a concentration 10 µM. JK-P3 decreases the proliferation of HCT116, SW480, and HT-29...
| Schlagworte: | 3,4-dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)-benzamide |
| Anwendung: | VEGFR2 inhibitor |
| CAS | 942655-44-9 |
| MW: | 323.4 D |
ab 96,00 €
