Zu "942425-68-5" wurden 2 Artikel gefunden!
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PHA-767491 hydrochloride
Artikelnummer: TGM-T6940-100mg
Description: PHA-767491 hydrochloride (CAY-10572 hydrochloride) is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against GSK3-beta and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1. Target: GSK-3, CDK, Apoptosis....
| Schlagworte: | CAY-10572 hydrochloride, CAY10572, PHA-767491, PHA767491 HCl |
| Anwendung: | Cdc7 kinase inhibitor |
| CAS | 942425-68-5 |
| MW: | 249.69 D |
ab 43,00 €
PHA-767491 (hydrochloride)
Artikelnummer: Cay18218-10
Cdc7 kinase is a key regulator of the S-phase of the cell cycle. It is known to promote the activity of DNA replication origins in eukaryotic organisms. Inhibition of Cdc7 kinase causes blockade of DNA synthesis in human cell lines. Tumor cells are then funneled into the apoptotic pathway in a p53-independent...
| Schlagworte: | CAY10572, 1,5,6,7-tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one, monohydrochloride |
| Anwendung: | Cdc7 kinase inhibitor |
| CAS | 942425-68-5 |
| MW: | 249.7 D |
ab 66,00 €
