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SCH 772984
Artikelnummer: Cay19166-1
The extracellular regulated kinases 1 and 2 (ERK1/2) are functionally redundant kinases activated by a variety of growth factors and mitogens. SCH 772984 is a potent inhibitor of ERK1 and ERK2 (IC50s = 4 and 1 nM, respectively). It is highly selective, with only seven kinases of 300 tested showing more than 50%...
| Schlagworte: | (3R)-1-[2-oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxa... |
| Anwendung: | Potent ERK1 / ERK2 inhibitor |
| CAS | 942183-80-4 |
| MW: | 587.7 D |
ab 52,00 €
SCH772984
Artikelnummer: TGM-T6066-2mg
Description: SCH772984 is an ERK inhibitor that inhibits ERK1 and ERK2 (IC50=4/1 nM) and is highly selective and ATP-competitive. SCH772984 exhibits antitumor activity against BRAF or RAS mutant cells. Target: MEK, ERK. Smiles: O=C(CN1CC[C@H](C1)C(=O)Nc1ccc2[nH]nc(-c3ccncc3)c2c1)N1CCN(CC1)c1ccc(cc1)-c1ncccn1....
| Anwendung: | Potent ERK1 / ERK2 inhibitor |
| CAS | 942183-80-4 |
| MW: | 587.67 D |
ab 48,00 €
SCH-772984
Artikelnummer: LKT-S0929.1
ERK1/2 inhibitor.
| Schlagworte: | SCH772984 |
| Anwendung: | Potent ERK1 / ERK2 inhibitor |
| CAS | 942183-80-4 |
| MW: | 587.69 D |
ab 80,00 €
