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Pavinetant
Artikelnummer: TGM-T16114-100mg
Description: Pavinetant (MLE-4901) is an orally available neurokinin-3 receptor (NK3R) antagonist used to improve menopausal symptoms. Target: Neurokinin receptor. Smiles: CC[C@H](NC(=O)c1c(NS(C)(=O)=O)c(nc2ccccc12)-c1ccccc1)c1ccccc1. References: Li Y, et al. In vitro assessment of metabolic drug-drug interaction...
| Schlagworte: | AZD2624, MLE-4901, AZD4901 |
| Anwendung: | Targets tachykinin receptor 3 (TACR3) |
| CAS | 941690-55-7 |
| MW: | 459.56 D |
ab 74,00 €
MLE-4901
Artikelnummer: Cay23587-1
MLE-4901 is an antagonist of the neurokinin-3 (NK3) receptor. It inhibits human liver microsomal CYP3A4/5 with apparent IC50 values of 7.1 and 19.8 µM in midazolam 1'-hydroxylation and testosterone 6beta-hydroxylation assays, respectively.Formal Name:...
| Schlagworte: | AZD 2624, AZD 4901, 3-[(methylsulfonyl)amino]-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide |
| Anwendung: | Neurokinin-3 (NK3) receptor antagonist |
| CAS | 941690-55-7 |
| MW: | 459.6 D |
ab 94,00 €
