Zu "939791-38-5" wurden 2 Artikel gefunden!
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PF-562271 (besylate)
Artikelnummer: Cay18499-1
Focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) are non-receptor tyrosine kinases that constitute the FAK subfamily and play a vital role in many oncogenic pathways. PF-562271 is an ATP-competitive, reversible inhibitor of FAK (IC50 = 1.5 nM) that demonstrates 10-fold reduced potency for PYK2...
| Schlagworte: | N-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-m... |
| Anwendung: | FAK inhibitor |
| CAS | 939791-38-5 |
| MW: | 665.7 D |
ab 56,00 €
PF-562271 besylate
Artikelnummer: TGM-T6177-100mg
Description: PF-562271 besylate (PF-00562271 Besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Target: CDK, FAK, PYK2. Smiles:...
| Schlagworte: | PF-00562271 Besylate |
| Anwendung: | FAK inhibitor |
| CAS | 939791-38-5 |
| MW: | 665.66 D |
ab 31,00 €
