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FIPI
Artikelnummer: Cay13563-1
Isoforms of phospholipase D (PLD) cleave the head group from phospholipids, releasing the second messenger phosphatidic acid (PA), which can produce changes in Ras activation, cell spreading, stress fiber formation, chemotaxis, and membrane vesicle trafficking. FIPI is a derivative of halopemide which potently...
| Schlagworte: | 5-Fluoro-2-Indolyl des-Chlorohalopemide,... |
| Anwendung: | PLD1/PLD2 inhibitor |
| CAS | 939055-18-2 |
| MW: | 421.5 D |
ab 67,00 €
FIPI
Artikelnummer: TGM-T3580-2mg
Description: FIPI (5-Fluoro-2-indolyl deschlorohalopemide) is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM), prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. Target: Phospholipase, Autophagy. Smiles:...
| Schlagworte: | 5-Fluoro-2-indolyl deschlorohalopemide |
| CAS | 939055-18-2 |
| MW: | 421.47 D |
ab 40,00 €
