Zu "937270-47-8" wurden 2 Artikel gefunden!
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SB-1317
Artikelnummer: Cay26817-10
SB-1317 is a multi-kinase inhibitor. It inhibits Cdk1, -2, -3, -5, and -9 (IC50s = 3-9 nM), as well as JAK family kinases (IC50s = 14-59 nM), wild-type and mutant FLT3s (IC50s = 19-27 nM), and Src family kinases (IC50s = 11-15 nM). SB-1317 inhibits proliferation in a panel of 12 liquid and six solid tumor cell lines...
| Schlagworte: | TG02, Zotiraciclib,... |
| Anwendung: | Multi-kinase inhibitor |
| CAS | 937270-47-8 |
| MW: | 372.5 D |
ab 128,00 €
(E/Z)-Zotiraciclib
Artikelnummer: TGM-T21503-100mg
Description: (E/Z)-Zotiraciclib ((E/Z)-TG02) effectively inhibits CDK2, JAK2, and FLT3 with IC50s of 13 nM, 73 nM, and 56 nM, respectively. Target: CDK, FLT, JAK. Smiles: CN1CC2=CC(N=C3NC(C=4C=C(C=CC4)OCCC=CC1)=CC=N3)=CC=C2. References: William AD, et al. Discovery of kinase spectrum selective macrocycle...
| Schlagworte: | (E/Z)-SB1317, (E/Z)-TG02 |
| CAS | 937270-47-8 |
| MW: | 372.46 D |
ab 37,00 €
