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OXA-01
Artikelnummer: Cay20456-1
OXA-01 is an inhibitor of both mTORC1 and mTORC2 (IC50s = 11 and 29 nM, respectively). It is selective for mTOR over PI3K isoforms and DNA protein kinase. OXA-01 reduces VEGF production in tumors in association with decreased vessel sprouting.Formal Name:...
| Schlagworte: | trans-4-[8-amino-1-(7-chloro-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-cyclohexanecarboxylic acid |
| Anwendung: | Dual mTORC1 / mTORC2 inhibitor |
| CAS | 936889-68-8 |
| MW: | 409.9 D |
ab 49,00 €
OXA-01
Artikelnummer: TGM-T21816-10mg
Description: OXA-01 is a potent mTORC1 (IC50: 29 nM) and mTORC2 (IC50: 7 nM) inhibitor, demonstrating broad anti-tumor activity [1]. Target: Others. Smiles: Nc1nccn2c(nc(-c3cc4cccc(Cl)c4[nH]3)c12)[C@H]1CC[C@@H](CC1)C(O)=O
| CAS | 936889-68-8 |
| MW: | 409.87 D |
ab 106,00 €
