Zu "934493-76-2" wurden 3 Artikel gefunden!
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XL-765
Artikelnummer: LKT-X4424.1
PI3K and mTOR inhibitor.
| Schlagworte: | XL765, Voxtalisib, SAR245409 |
| Anwendung: | PI3K and mTOR inhibitor |
| CAS | 934493-76-2 |
| MW: | 270.29 D |
ab 204,00 €
Voxtalisib
Artikelnummer: Cay30323-10
Voxtalisib is a dual inhibitor of PI3K and mammalian target of rapamycin complex (mTORC, IC50s = 39, 110, 43, 9, 160, and 910 nM for PI3Kalpha, PI3Kbeta, PI3Kdelta, PI3Kgamma, mTORC1, and mTORC2, respectively). It is selective for these kinases over vacuolar protein sorting 34 (VPS34, IC50 = 9,100 nM) and a panel of...
| Schlagworte: | SAR245409, XL765, 2-amino-8-ethyl-4-methyl-6-(1H-pyrazol-3-yl)-pyrido[2,3-d]pyrimidin-7(8H)-one |
| Anwendung: | mTORC / PI3K dual inhibitor |
| CAS | 934493-76-2 |
| MW: | 270.3 D |
ab 174,00 €
Voxtalisib
Artikelnummer: TGM-T7014-100mg
Description: Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110gamma with IC50 of 9 nM, also inhibits DNA-PK and mTOR. Phase 1/2. Target: DNA-PK, PI3K, mTOR. Smiles: CCn1c2nc(N)nc(C)c2cc(-c2cc[nH]n2)c1=O. References: Garcia-Echeverria C, et al. Oncogene, 2008, 27(41), 5511-5526.
| Schlagworte: | SAR245409, XL765 |
| Anwendung: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta |
| CAS | 934493-76-2 |
| MW: | 270.29 D |
ab 31,00 €
