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HSP-990
Artikelnummer: Cay19149-1
The heat shock proteins (Hsps) act as molecular chaperones. Hsp90 is an abundant protein with roles in protein folding, cell signaling, and cancer. HSP-990 is an Hsp90 inhibitor with IC50 values of 0.6, 0.8, and 8.5 nM for Hsp90alpha, Hsp90beta, and GRP94, respectively. It inhibits the TRAP1 ATPase with an IC50...
| Schlagworte: | NVP-HSP990, (7R)-2-amino-7-[4-fluoro-2-(6-methoxy-2-pyridinyl)phenyl]-7,8-dihydro-4-methyl-pyrido[4,3-d]pyrimidin-5(6H)-one |
| Anwendung: | Hsp90 inhibitor |
| CAS | 934343-74-5 |
| MW: | 379.4 D |
ab 56,00 €
NVP-HSP990
Artikelnummer: TGM-T6118-100mg
Description: NVP-HSP990 (HSP990) is an effective and specific HSP90alpha/beta inhibitor (IC50: 0.6 /0.8 nM). Target: Apoptosis, HSP. Smiles: COC1=CC=CC(=N1)C1=C(C=CC(F)=C1)C1CC2=C(C(C)=NC(N)=N2)C(=O)N1. References: Menezes DL, et al. Mol Cancer Ther, 2012, 11(3), 730-739.
| Schlagworte: | HSP990 |
| Anwendung: | Hsp90 inhibitor |
| CAS | 934343-74-5 |
| MW: | 379.39 D |
ab 39,00 €
