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T5601640
Artikelnummer: Cay22140-1
T5601640 is an inhibitor of LIM kinase 2 (LIMK2) that inhibits LIMK2-mediated cofilin phosphorylation. It reduces the levels of phosphorylated cofilin (p-cofilin) in mouse embryonic fibroblasts (MEF) lacking neurofibromin (Nf1-/-, IC50 = 30 µM), which normally have high levels of p-cofilin. T5601640 (50 µM)...
| Schlagworte: | T56-LIM Kinase Inhibito, T56-LIMKi, 3-methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide |
| Anwendung: | LIMK2 inhibitor |
| CAS | 924473-59-6 |
| MW: | 389.3 D |
ab 51,00 €
NEU
T56-LIMKi
Artikelnummer: TGM-T3960-100mg
Description: T56-LIMKi (T5601640) is a selective inhibitor of LIMK2. Target: LIM Kinase. Smiles: Cc1cc(on1)C(=O)Nc1cccc(c1)C(=O)Nc1cccc(c1)C(F)(F)F. References: Rak R, et al. Novel LIMK2 Inhibitor Blocks Panc-1 Tumor Growth in a mouse xenograft model. Oncoscience. 2014 Jan 1,1(1):39-48. eCollection 2014.
| Schlagworte: | T5601640 |
| Anwendung: | LIMK2 inhibitor |
| CAS | 924473-59-6 |
| MW: | 389.33 D |
ab 39,00 €
