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L82-G17
Artikelnummer: Cay41041-10
L82-G17 is an uncompetitive inhibitor of DNA ligase I. It increases the retention of DNA ligase I, but not DNA ligase III, on nicked DNA-coated beads in a cell-free assay, as well as decreases the proliferation of HeLa cells when used at a concentration of 20 µM.Formal Name:...
| Schlagworte: | 4-chloro-5-(2-(3-hydroxybenzylidene)hydrazineyl)pyridazin-3(2H)-one |
| Anwendung: | DNA ligase I inhibitor |
| CAS | 92285-87-5 |
| MW: | 264.7 D |
ab 186,00 €
L82-G17
Artikelnummer: TGM-T9961-100mg
Description: L82-G17 is an uncompetitive LigI-selective inhibitor in human cells with utility as a probe of the catalytic activity and cellular functions of LigI. Target: DNA/RNA Synthesis. Smiles: Oc1cccc(\C=N\Nc2cn[nH]c(=O)c2Cl)c1. References: Howes TRL, et al. Structure-activity relationships among DNA ligase...
| Anwendung: | DNA ligase I inhibitor |
| CAS | 92285-87-5 |
| MW: | 264.67 D |
ab 30,00 €
