Zu "918504-65-1" wurden 4 Artikel gefunden!
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Vemurafenib, Free Base (PLX4032, R7204, RG7204,...
Artikelnummer: LC-V-2800_10g
Soluble in DMSO at 100 mg/mL, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 25-50 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
| Schlagworte: | RG-7204, Ro 51-85426, Vemurafenib,... |
| Anwendung: | B-Raf kinase (mutant V600E and wild type) inhibitor |
| CAS | 918504-65-1 |
| MW: | 489,92 D |
ab 88,00 €
PLX4032
Artikelnummer: Cay10618-5
PLX4032 is an orally bioavailable, ATP-competitive inhibitor of mutant V600E and wild type B-Raf kinases (IC50s = 31 and 100 nM, respectively). It inhibits cell proliferation in a variety of cell lines expressing B-Raf V600E and synergizes strongly with taxol, vinblastine, and oxaliplatin in inhibiting the...
| Schlagworte: | RG-7204, Ro 51-85426, Vemurafenib,... |
| Anwendung: | B-Raf kinase (mutant V600E and wild type) inhibitor |
| CAS | 918504-65-1 |
| MW: | 489.9 D |
ab 60,00 €
Vemurafenib
Artikelnummer: 022761.100
Vemurafenib selective BRAFV600E kinase inhibitor, an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or...
| CAS | 918504-65-1 |
ab 256,00 €
PLX-4032
Artikelnummer: SYN-1161-M001
Soluble in DMSO or ethanol. PLX4032 (Vemurafenib, RG7204, Zelboraf, RO5185426) is a novel and potent inhibitor of B-RafV600E with an IC(50) of 31nM. Target: Raf , Kinase Group: TKL , Substrate: Serine-Threonine
| Schlagworte: | Vemurafenib, RG7204, Zelboraf, RO5185426 |
| Anwendung: | B-Raf V600E inhibitor |
| CAS | 918504-65-1 |
| MW: | 489,9 D |
ab 66,00 €
