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7BIO
7BIO

Artikelnummer: AG-MR-C0020-M010

Soluble in DMSO or ethanol. Stock solutions can be made up to 10 mM in DMSO. Anticancer compound. Caspase-independent, non-apoptotic cell death inducer. ATP-competitive Flt3 inhibitor. Necrosis inducer. Aurora B and C kinase inhibitor. DYRK1A and DYRK 2 (Dual-specificity tyrosine phosphorylation-regulated...
Schlagworte: 7-Bromoindirubin-3'-oxime
Anwendung: Flt3 inhibitor
CAS 916440-85-2
MW: 356,2 D
ab 165,00 €
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7BIO
7BIO

Artikelnummer: Cay19619-10

7BIO is a derivative of indirubin (Cay-14155) that triggers a rapid cell death process that is distinct from apoptosis and devoid of cytochrome c release or caspase activation. Furthermore, in contrast to other indirubin derivatives, 7BIO has only marginal activity against the classic indirubin targets,...
Schlagworte: 7-Bromoindirubin-3'-oxime, 7-bromo-3-[1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one
Anwendung: FLT3 / DYRK1A / DYRK2 inhibitor
CAS 916440-85-2
MW: 356.2 D
ab 241,00 €
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7BIO
7BIO

Artikelnummer: TGM-T22012-100mg

Description: 7-bromoindirubin-3'-oxime (7BIO) is a caspase independent nonapoptotic cell death inducer. 7BIO is an inhibitor of FLT3, DYRK1A, DYRK2, Aurora B and Aurora C kinases. Target: Aurora Kinase, CDK, DYRK, GSK-3, FLT. Smiles: O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2c1cccc2Br
CAS 916440-85-2
MW: 356.17 D
ab 37,00 €
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