Zu "915385-81-8" wurden 2 Artikel gefunden!
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Opaganib
Artikelnummer: AG-CR1-3749-M025
Opaganib is a selective inhibitor of sphingosine kinase 2 (SPHK2, Ki = 9.8 µM), a lipid kinase that catalyzes formation of the lipid signaling molecule sphingosine 1-phosphate (S1P). S1P promotes cancer growth, and proliferation and pathological inflammation, including TNF-alpha signaling and other inflammatory...
| Schlagworte: | 3-(4-Chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide, ABC294640, Yeliva |
| Anwendung: | SPHK2 inhibitor |
| CAS | 915385-81-8 |
| MW: | 380.9 D |
ab 99,00 €
ABC294640
Artikelnummer: Cay10587-10
ABC294640 is an inhibitor of sphingosine kinase 2 (SPHK2, Ki = 9.8 µM). It inhibits SPHK2 (IC50 = 60 µM) without affecting SPHK1 activity up to 100 µM but does reduce SPHK1 isoform a (SPHK1a) protein levels in androgen-independent LNCaP (LNCaP-AI) cells via an SPHK1-indirect, proteasomal-dependent mechanism when...
| Schlagworte: | 3-(4-chlorophenyl)-N-(4-pyridinylmethyl)-tricyclo[3.3.1.13,7]decane-1-carboxamide |
| CAS | 915385-81-8 |
| MW: | 380.9 D |
ab 60,00 €
