Zu "914471-09-3" wurden 3 Artikel gefunden!
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INCB024360 Analog
Artikelnummer: BPS-27338-1
INCB024360 analog is an orally available hydroxyamidine and inhibitor of indoleamine 2,3- dioxygenase (IDO1), with an IC50 of 10 nM. It shows little activity against other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). INCB024360 analog displays potential immunomodulating and antineoplastic...
| Schlagworte: | 4-[(3-chloro-4-fluoroanilino)-nitrosomethylidene]-1,2,5-oxadiazol-3-amine, IDO inhibitor, |
| Anwendung: | IDO1 inhibitor |
| CAS | 914471-09-3 |
| MW: | 271.6 D |
ab 410,00 €
INCB024360 analog
Artikelnummer: Cay18265-10
Indoleamine 2,3-dioxygenase (IDO) metabolizes tryptophan to kynurenine, leading to the production of NAD+ via the kynurenine pathway. It has been implicated in mediating pathological immunosuppression associated with certain diseases, including cancer. INCB024360 analog is a potent IDO1 inhibitor that demonstrates...
| Schlagworte: | IDO5L, 4-amino-N'-(3-chloro-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide |
| Anwendung: | IDO1 inhibitor |
| CAS | 914471-09-3 |
| MW: | 271.6 D |
ab 103,00 €
IDO5L
Artikelnummer: TGM-T2647-100mg
Description: IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM). Target: IDO, Indoleamine 2,3-Dioxygenase (IDO). Smiles: Nc1nonc1\C(Nc1ccc(F)c(Cl)c1)=N/O. References: Yue EW, et al. J Med Chem. 2009, 52(23), 7364-7367.
| Schlagworte: | INCB14943, INCB024360 analogue |
| CAS | 914471-09-3 |
| MW: | 271.64 D |
ab 30,00 €
