Zu "914382-60-8" wurden 2 Artikel gefunden!
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Tefinostat
Artikelnummer: Cay43665-1
An inhibitor of HDACs and a prodrug form of CHR-2847, increases intracellular protein acetylation in CD14+ primary human AML cells and gammaH2AX levels in primary CMML cells, selectively inhibits the growth of primary AML cells over normal bone marrow cells at 500 nM, induces beta-oxidation of hexacosanoic acid in...
| Schlagworte: | alphaS-[[[4-[[8-(hydroxyamino)-1,8-dioxooctyl]amino]phenyl]methyl]amino]-benzeneacetic acid, cyclopentyl ester |
| Anwendung: | HDAC inhibitor, CHR-2847 prodrug |
| CAS | 914382-60-8 |
| MW: | 495.62 D |
ab 118,00 €
Tefinostat
Artikelnummer: TGM-T17028-100mg
Description: Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor that is cleaved to the active acid CHR-2847 by intracellular esterase human carboxylesterase-1 (hCE-1). Tefinostat exhibits antitumor activity and can be used in the study of leukemia and advanced...
| Schlagworte: | CHR-2845 |
| CAS | 914382-60-8 |
| MW: | 495.61 D |
ab 91,00 €
