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9-amino-CPT
9-amino-CPT

Artikelnummer: TGM-T3S1957-100mg

Description: 9-amino-CPT (Aminocamptothecin) is an inhibitor of topoisomerase I with potent anticancer activity. Target: Topoisomerase. Smiles: CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cccc(N)c4cc3Cn1c2=O. References: de Souza PL, et al. 9-Aminocamptothecin: a topoisomerase I inhibitor with preclinical activity in prostate...
Schlagworte: 9-amino-2(S)-camptothecin, Aminocamptothecin, 9-Aminocamptothecin
Anwendung: Topoisomerase I inhibitor
CAS 91421-43-1
MW: 363.37 D
ab 37,00 €
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9-amino Camptothecin
9-amino Camptothecin

Artikelnummer: Cay17232-10

DNA topoisomerases relax supercoiled DNA during replication, transcription, recombination, repair, and chromosome condensation. The relaxation of DNA supercoiling by topoisomerase I at single-strand breaks represents a target for anticancer agents to intercalate between DNA base pairs, leading to the activation of...
Schlagworte: NSC 603071, (4S)-10-amino-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Anwendung: Topoisomerase I inhibitor
CAS 91421-43-1
MW: 363.4 D
ab 44,00 €
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