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A 83-01
Artikelnummer: Cay9001799-10
A 83-01 is an inhibitor of TGF-beta type I receptor kinase (ALK5), activin type IB receptor (ALK4), and nodal type I receptor (ALK7) (IC50s = 12, 45, and 7.5 nM, respectively). It blocks the phosphorylation of SMAD2/3 and inhibits TGF-beta-induced epithelial-to-mesenchymal transition. It has little effect on bone...
| Schlagworte: | 3-(6-methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide |
| Anwendung: | TGFBR1 inhibitor |
| CAS | 909910-43-6 |
| MW: | 421.5 D |
ab 49,00 €
A 83-01
Artikelnummer: LKT-A001001.5
| Schlagworte: | A83-01, ALK5 Inhibitor IV, 1H-Pyrazole-1-carbothioamide,3-(6-methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-,... |
| Anwendung: | TGFBR1 inhibitor |
| CAS | 909910-43-6 |
| MW: | 421.52 D |
ab 109,00 €
A 83-01
Artikelnummer: TGM-T3031-5mg
Description: A 83-01 (ALK5 Inhibitor IV) is an inhibitor of the TGF-beta type I receptors ALK5, ALK4, and ALK7 (IC50=12/45/7.5 nM). A 83-01 promotes the reprogramming of mouse fibroblasts into iPSCs. A 83-01 can be used in organoid cultures. Target: ALK, TGF-beta/Smad. Smiles:...
| Schlagworte: | A8301, ALK5 Inhibitor IV |
| Anwendung: | TGFBR1 inhibitor |
| CAS | 909910-43-6 |
| MW: | 421.52 D |
ab 49,00 €
