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Inflachromene
Artikelnummer: Cay17006-10
Inflachromene is an anti-inflammatory agent that directly binds high mobility group protein 1 (HMGB1) and HMGB2 and reduces their cytoplasmic accumulation in microglial cells. It is functional in vivo, downregulating proinflammatory functions of HMGB proteins and reducing neuronal damage. Inflachromene also...
| Schlagworte: | ICM, 5,12b-dihydro-10-hydroxy-7,7-dimethyl-2-phenyl-1H,7H-[1]benzopyrano[4,3-c][1,2,4]triazolo[1,2-a]pyridazine-1,3(2H)-dione |
| Anwendung: | Microglial inhibitor |
| CAS | 908568-01-4 |
| MW: | 377.4 D |
ab 205,00 €
Inflachromene
Artikelnummer: TGM-T24167-100mg
Description: Inflachromene (ICM) is an inhibitor of HMGB1 and HMGB expression with anti-inflammatory activity.Inflachromene reduces seizure severity in a mouse model of epilepsy by inhibiting HMGB1 translocation, inhibits endothelial proliferation through the HMGB1/2-regulated TLR4-NF-kappaB pathway, and inhibits...
| Schlagworte: | ICM |
| CAS | 908568-01-4 |
| MW: | 377.39 D |
ab 110,00 €
