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SMU127
Artikelnummer: Cay33147-1
SMU127 is an agonist of the toll-like receptor 1/2 (TLR1/2) heterodimer. It induces NF-kappaB signaling in cells expressing human TLR2 (EC50 = 0.55 µM) but not cells expressing human TLR3, -4, -5, -7, or -8 when used at concentrations ranging from 0.1 to 100 µM. SMU127 induces the production of TNF-alpha in isolated...
| Schlagworte: | ZINC666243, 5,6-dihydro-2-[[(4-methyl-1-piperazinyl)carbonyl]amino]-4H-cyclopenta[b]thiophene-3-carboxylic acid, ethyl ester |
| Anwendung: | TLR1/2 agonist |
| CAS | 903864-87-9 |
| MW: | 337.4 D |
ab 126,00 €
SMU127
Artikelnummer: TGM-T35672-1mg
Description: SMU127 is an agonist of the toll-like receptor 1/2 (TLR1/2) heterodimer. Target: Others. Smiles: C(OCC)(=O)C=1C2=C(SC1NC(=O)N3CCN(C)CC3)CCC2. References: Chen, Z., Cen, X., Yang, J., et al.Structure-based discovery of a specific TLR1-TLR2 small molecule agonist from the ZINC drug library databaseChem....
| Anwendung: | TLR1/2 agonist |
| CAS | 903864-87-9 |
| MW: | 337.44 D |
ab 271,00 €
