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Pitolisant hydrochloride
Artikelnummer: TGM-T7176-100mg
Description: Pitolisant hydrochloride (Ciproxidine) is a potent and selective inverse agonist of the histamine H3 receptor(Ki : 0.16 nM). Target: Histamine Receptor. Smiles: Cl.Clc1ccc(CCCOCCCN2CCCCC2)cc1. References: Kotanska Magdalena, Kuder K J , Szczepanska Katarzyna, et al. The histamine H3 receptor inverse...
| Schlagworte: | Ciproxidine, BF 2649 |
| Anwendung: | Targets histamine receptor H3 (HRH3) |
| CAS | 903576-44-3 |
| MW: | 332.31 D |
ab 43,00 €
Pitolisant
Artikelnummer: Cay19307-1
Pitolisant is a nonimidazole histamine H3 receptor antagonist (Ki = 0.16 nM) and inverse agonist (EC50 = 1.5 nM). It increases the levels of tele-methylhistamine in mouse brain, indicating histaminergic neuron activity, with an ED50 value of 1.6 mg/kg. Pitolisant also increases dopamine and acetylcholine levels in...
| Schlagworte: | BF 2649, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine, monohydrochloride |
| Anwendung: | Histamine H3 receptor antagonist / inverse agonist |
| CAS | 903576-44-3 |
| MW: | 332.3 D |
ab 52,00 €
