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PIK-294
Artikelnummer: Cay23427-1
PIK-294 is a potent inhibitor of the phosphatidylinositol 3-kinase (PI3K) catalytic subunit p110delta (IC50s = 10,000, 490, 10, and 160 nM, for p110 subunit isoforms alpha, beta, delta, and gamma, respectively). It is selective for PI3K p110 subunit isoforms over DNA-PK, mTOR, and eight tyrosine kinases tested. It...
| Schlagworte: | 2-[[4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone |
| Anwendung: | PI3K p110 delta inhibitor |
| CAS | 900185-02-6 |
| MW: | 489.5 D |
ab 44,00 €
PIK-294
Artikelnummer: SYN-1098-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. PIK-294 is a PI3 Kinase inhibitor that is 20- to 60-fold more potent than the parent compound, PIK-293. It is one of the most potent p110delta-selective inhibitors that has been reported, with an IC(50) of 10nM. Target: PI3K , Kinase Group: Lipid Kinase ,...
| Schlagworte: | PIK294 |
| Anwendung: | PI3K p110 delta inhibitor |
| CAS | 900185-02-6 |
| MW: | 489,5 D |
ab 162,00 €
PIK-294
Artikelnummer: LKT-P3441.1
PIK294 is an inhibitor of PI3K that is somewhat selective for p110 PI3K and less sensitive to p110 PI3K.
| Anwendung: | PI3K p110 delta inhibitor |
| CAS | 900185-02-6 |
| MW: | 489.53 D |
ab 66,00 €
PIK-294
Artikelnummer: TGM-T2297-100mg
Description: PIK-294 is a excellently specific p110delta inhibitor(IC50=10 nM). Target: PI3K. Smiles: Cc1ccccc1-n1c(Cn2nc(-c3cccc(O)c3)c3c(N)ncnc23)nc2cccc(C)c2c1=O. References: Knight ZA, et al. Cell. 2006, 125(4), 733-747.
| Schlagworte: | PIK294 |
| CAS | 900185-02-6 |
| MW: | 489.53 D |
ab 31,00 €
