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BD750
Artikelnummer: TGM-T8546-100mg
Description: BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 µM and 1.1 µM in mouse and human T cells, respectively). Target: JAK, STAT. Smiles: Oc1c2CCCCc2nn1-c1nc2ccccc2s1. References: Yan Zhou, et al. Tolerogenic...
| CAS | 892686-59-8 |
| MW: | 271.34 D |
ab 46,00 €
BD 750
Artikelnummer: Cay37574-10
BD 750 is an immunosuppressant. It inhibits the proliferation of primary human and mouse T cells (IC50s = 1.1 and 1.5 µM, respectively) without inducing cytotoxicity when used at concentrations ranging from 3.13 to 50 µM. BD 750 induces cell cycle arrest at the G0/G1 phases in CD3 and CD28 antibody-activated primary...
| Schlagworte: | 2-(2-benzothiazolyl)-4,5,6,7-tetrahydro-2H-indazol-3-ol |
| Anwendung: | Immunosuppressant |
| CAS | 892686-59-8 |
| MW: | 271.3 D |
ab 40,00 €
