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ML-349
Artikelnummer: Cay20923-1
ML-349 is a selective and reversible inhibitor of lysophospholipase 2 (LYPLA2, Kis = 230 and >10,000 nM for human recombinant LYPLA2 and LYPLA1, respectively). Treatment with ML-349 results in >95% inhibition of LYPLA2 with no change in the activity of 25 other serine hydrolases in BW5147 murine T cell hybridoma...
| Schlagworte: | (5,5-dioxido-4H-thieno[3,2-c][1]benzothiopyran-2-yl)[4-(4-methoxyphenyl)-1-piperazinyl]-methanone |
| Anwendung: | LYPLA2 inhibitor |
| CAS | 890819-86-0 |
| MW: | 454.6 D |
ab 49,00 €
ML349
Artikelnummer: TGM-T16108-10mg
Description: ML349 is an inhibitor of LYPLA2 (IC50: 144 nM). ML349 is an effective and specific acyl protein thioesterase 2 (APT-2) inhibitor (Ki: 120 nM). Target: Phospholipase, Others. Smiles: COc1ccc(cc1)N1CCN(CC1)C(=O)c1cc2CS(=O)(=O)c3ccccc3-c2s1. References: Won SJ, et al. Molecular Mechanism for...
| Anwendung: | LYPLA2 inhibitor |
| CAS | 890819-86-0 |
| MW: | 454.56 D |
ab 30,00 €
