Zu "890764-36-0" wurden 2 Artikel gefunden!
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VU29
Artikelnummer: Cay43928-1
VU29 is a positive allosteric modulator (PAM) of metabotropic glutamate receptor 5 (mGluR5, Ki = 250 nM). It potentiates glutamate-induced calcium flux in primary rat cortical astrocytes (EC50 = 10. nM). VU29 (30 mg/kg) prevents ethanol-induced memory impairments in the novel object recognition test in rats. It also...
| Schlagworte: | N-(1,3-diphenyl-1H-pyrazol-5-yl)-4-nitro-benzamide |
| Anwendung: | Positive allosteric mGluR5 modulator |
| CAS | 890764-36-0 |
| MW: | 384.4 D |
ab 38,00 €
VU-29
Artikelnummer: TGM-T23515-100mg
Description: VU-29 is a positive allosteric mGlu5 receptor modulator with an EC50 of 9 nM and a Ki of 244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes [EC50: rmGluR1/rmGluR2=557 nM/1.5 µM, hmGluR4=154 nM]. Target: GluR. Smiles:...
| Schlagworte: | VU 29 |
| CAS | 890764-36-0 |
| MW: | 384.39 D |
ab 29,00 €
