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CCT128930
Artikelnummer: Cay18194-1
CCT128930 is an ATP-competitive inhibitor of Akt2 (IC50 = 6 nM). It is selective for Akt over a panel of 47 other kinases, including the related protein kinase A and p70S6K. CCT128930 blocks the phosphorylation of Akt targets, inhibits proliferation of multiple tumor cell lines in vitro, and prevents the growth of...
| Schlagworte: | 4-[(4-chlorophenyl)methyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinamine |
| Anwendung: | ATP-competitive Akt2 inhibitor |
| CAS | 885499-61-6 |
| MW: | 341.8 D |
ab 38,00 €
CCT-128930
Artikelnummer: LKT-C1176.1
Pyrrolopyrimidine, Akt inhibitor.
| Schlagworte: | CCT128930 |
| Anwendung: | Pyrrolopyrimidine, Akt inhibitor |
| CAS | 885499-61-6 |
| MW: | 341.84 D |
ab 141,00 €
CCT128930
Artikelnummer: TGM-T6303-100mg
Description: CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase. Target: S6 Kinase, Akt, Apoptosis, Autophagy, PKA. Smiles: NC1(Cc2ccc(Cl)cc2)CCN(CC1)c1ncnc2[nH]ccc12. References: Yap TA, et al. Mol...
| Anwendung: | ATP-competitive Akt2 inhibitor |
| CAS | 885499-61-6 |
| MW: | 341.84 D |
ab 34,00 €
