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HJC0350
Artikelnummer: TGM-T6536-100mg
Description: HJC0350 is an effective and specific EPAC2 inhibitor (IC50: 0.3 µM), and no inhibition of Epac1. Target: cAMP. Smiles: Cc1cc(C)n(c1)S(=O)(=O)c1c(C)cc(C)cc1C. References: Chen H, et al. J Med Chem. 2013, 56(3), 952-962.
| Anwendung: | RAPGEF4 inhibitor |
| CAS | 885434-70-8 |
| MW: | 277.38 D |
ab 31,00 €
HJC0350
Artikelnummer: Cay22949-1
HJC0350 is a selective inhibitor of exchange protein directly activated by cAMP 2 (Epac2) with an IC50 value of 300 nM for competition with 8-NBD-cAMP binding. It inhibits Epac2 guanine nucleotide exchange activity but does not inhibit Epac1-mediated Rap1-GDP exchange or cAMP-mediated protein kinase A (PKA)...
| Schlagworte: | 2,4-dimethyl-1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-pyrrole |
| Anwendung: | RAPGEF4 inhibitor |
| CAS | 885434-70-8 |
| MW: | 277.4 D |
ab 44,00 €
