Zu "883976-12-3" wurden 2 Artikel gefunden!
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M8-B (hydrochloride)
Artikelnummer: Cay21646-1
M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin (Cay-10137), or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively). It displays no effect at other TRP channels. M8-B decreases deep body temperature in wild-type mice and rats but has no...
| Schlagworte: | N-(2-aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide, monohydrochloride |
| Anwendung: | TRPM8 antagonist |
| CAS | 883976-12-3 |
| MW: | 433 D |
ab 51,00 €
M8-B Hydrochloride
Artikelnummer: TGM-T8442-100mg
Description: M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist. Target: TRP/TRPV Channel. Smiles: Cl.COc1cc(CN(CCN)C(=O)c2cccs2)ccc1OCc1ccccc1. References: Zandi N , Zaniani N R , Moghimi A , et al. Protective effects of M8-B, a TRPM8 antagonist, on febrile- and...
| Anwendung: | TRPM8 antagonist |
| CAS | 883976-12-3 |
| MW: | 432.96 D |
ab 30,00 €
