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A2793
Artikelnummer: Cay41081-1
A2793 is an inhibitor of the two-pore domain potassium channel K2P18.1/TRESK (IC50 = 6.8 µM in ionomycin-stimulated Xenopus oocytes expressing the mouse receptor). It is selective for K2P18.1/TRESK over K2P2.1/TREK1, K2P10.1/TREK2, K2P4.1/TRAAK, K2P3.2/TASK2, K2P3.3/TASK3, K2P16.1/TALK1, and K2P13.1/THIK1 at 100 µM...
| Schlagworte: | 2-[(5-chloro-8-quinolinyl)oxy]-acetic acid, ethyl ester |
| Anwendung: | K2P18.1/TRESK blocker |
| CAS | 88349-90-0 |
| MW: | 265.7 D |
ab 42,00 €
A2793
Artikelnummer: TGM-T7774-100mg
Description: A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 µM. It is more selective for TRESK, and relatively weaker for TREK-1 and TALK-1. Target: Potassium Channel. Smiles: CCOC(=O)COC1=CC=C(Cl)C2=CC=CN=C12
| Anwendung: | K2P18.1/TRESK blocker |
| CAS | 88349-90-0 |
| MW: | 265.69 D |
ab 39,00 €
