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INF 4E
INF 4E

Artikelnummer: Cay42315-10

An NLRP3 inflammasome inhibitor, inhibits NLRP3 inflammasome by 51.8% at 10 µM, inhibits caspase 1 (Ki = 10.6 µM), active against S. aureus, C. diphtheriae, K. pneumoniae, and E. coli, (MICs = 18, 18, 18, and 16 µg/ml, respectively) and the fungus C. albicans (MIC = 13 µg/ml), inhibits ATP-induced pyroptosis in...
Schlagworte: 2-chloro-beta-hydroxy-a-methylene-benzenepropanoic acid, ethyl ester
Anwendung: NLRP3 inflammasome inhibitor
CAS 88039-46-7
MW: 240.68 D
ab 116,00 €
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NLRP3-IN-9
NLRP3-IN-9

Artikelnummer: TGM-T28178-100mg

Description: NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner. Target: NOD. Smiles:...
Schlagworte: INF4E, INF 4E, INF-4E
CAS 88039-46-7
MW: 240.68 D
ab 34,00 €
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