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Fostriecin (sodium salt)
Artikelnummer: Cay14749-100
Fostriecin is an inhibitor of the serine/threonine protein phosphatases 2A (PP2A) and 4 (PP4) (IC50s = 3.2 and 3 nM, respectively). It less effectively inhibits topoisomerase II and PP1 (IC50s = 40 and 131 µM, respectively) and does not inhibit PP2B. Through its effects on protein phosphatases, fostriecin increases...
| Schlagworte: | Antibiotic CI-920, Phosphotrienin,... |
| Anwendung: | PP2A/PP4 inhibitor |
| CAS | 87860-39-7 |
| MW: | 452.4 D |
ab 541,00 €
Fostriecin
Artikelnummer: AG-CN2-0057-C010
Antibiotic. Anticancer compound. Anti-fungal. Catalytic inhibitor of topoisomerase II (IC50 = 40 µM). Potent protein phosphatase 2A (PP2A) (IC50 = 1. 5 nM) and 4 (PP4) (IC50 = 3 nM) inhibitor. Weak protein phosphatase type 1 (PP1) inhibitor (IC50=131µM). No apparent inhibition on PP2B. Mitotic entry checkpoint...
| Schlagworte: | Phosphotrienin, CI-920, CL-1565A, NSC-339638, PD 110,161, Pyranone phosphate |
| Anwendung: | Ser/Thr phosphatase inhibitor |
| CAS | 87860-39-7 |
| MW: | 452,4 D |
209,00 €
