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JNJ 303
JNJ 303

Artikelnummer: TGM-T7653-100mg

Description: JNJ 303 is a potent blocker of IKs (IC50 : 64 nM). Target: Potassium Channel. Smiles: CC(C)(Oc1ccc(Cl)cc1)C(=O)N[C@H]1[C@H]2C[C@H]3C[C@@H]1C[C@](C3)(C2)NS(C)(=O)=O. References: Kang C , Badiceanu A , Brennan J A , et al. beta-adrenergic stimulation augments transmural dispersion of repolarization via...
Anwendung: Kv7.1 inhibitor
CAS 878489-28-2
MW: 440.98 D
ab 42,00 €
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JNJ-303
JNJ-303

Artikelnummer: Cay37345-25

JNJ-303 is an inhibitor of voltage-gated potassium channel Kv7.1 (IC50 = 0.064 µM). It is selective for inhibiting Kv7.1 currents (IKs) over INa, IKr, Ito, IK1, and ICaL (IC50s =3.3, 12.6, 11.1, >100, and >10 µM, respectively). It selectively inhibits the heteromeric Kv7.1-KCNE1 complex (IC50 = 0.0784 µM) with no...
Schlagworte: 2-(4-chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide, stereoisomer
Anwendung: Kv7.1 inhibitor
CAS 878489-28-2
MW: 441 D
ab 54,00 €
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JNJ-303
JNJ-303

Artikelnummer: Cay37345-10

JNJ-303 is an inhibitor of voltage-gated potassium channel Kv7.1 (IC50 = 0.064 µM). It is selective for inhibiting Kv7.1 currents (IKs) over INa, IKr, Ito, IK1, and ICaL (IC50s =3.3, 12.6, 11.1, >100, and >10 µM, respectively). It selectively inhibits the heteromeric Kv7.1-KCNE1 complex (IC50 = 0.0784 µM) with no...
Schlagworte: 2-(4-chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide, stereoisomer
Anwendung: Kv7.1 inhibitor
CAS 878489-28-2
MW: 441 D
ab 213,00 €
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