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F-Amidine (trifluoroacetate salt)
F-Amidine (trifluoroacetate salt)

Artikelnummer: Cay10610-250

F-amidine is an inhibitor of protein arginine deiminases (PADs) that is selective for PAD1 and PAD4 (IC50s = 29.5, 350, and 21.6 µM for PAD1, PAD3, and PAD4 in vitro, respectively). It irreversibly inactivates all four PAD subtypes (kinact/KI = 2,800, 380, 170, and 3,000 M-1min-1 by covalently modifying an active...
Schlagworte: N-[(1S)-1-(aminocarbonyl)-4-[(2-fluoro-1-iminoethyl)amino]butyl]-benzamide, 2,2,2-trifluoroacetate
Anwendung: Peptidyl arginine deiminase (PAD) inhibitor
CAS 877617-46-4
MW: 408.4 D
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