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AIM 100
Artikelnummer: Cay29487-5
AIM 100 is an inhibitor of activated Cdc42 kinase 1/tyrosine non-receptor kinase 2 (ACK1/TNK2, IC50 = 21.58 nM). It is selective for ACK1/TNK2 over Abl1, BTK, LCK, and LYN (IC50s = 705.9, 871.7, 432.3, and 346.7 nM, respectively), as well as a panel of 25 additional kinases. AIM 100 (1 µM) inhibits EGF-induced...
| Schlagworte: | 5,6-diphenyl-N-[[(2S)-tetrahydro-2-furanyl]methyl]-furo[2,3-d]pyrimidin-4-amine |
| Anwendung: | ACK1/TNK2 inhibitor |
| CAS | 873305-35-2 |
| MW: | 371.4 D |
ab 139,00 €
AIM-100
Artikelnummer: TGM-T5092-100mg
Description: AIM-100 is a Ack1 inhibitor (IC50: 24 nM). Target: ACK. Smiles: C(Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1)C1CCCO1. References: Mahajan K, et al. Ack1 tyrosine kinase activation correlates with pancreatic cancer progression. Am J Pathol. 2012 Apr,180(4):1386-93.
| Schlagworte: | AIM100 |
| Anwendung: | ACK1/TNK2 inhibitor |
| CAS | 873305-35-2 |
| MW: | 371.43 D |
ab 40,00 €
