Zu "871362-31-1" wurden 2 Artikel gefunden!
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CTEP
Artikelnummer: Cay28773-10
CTEP is an inverse agonist of metabotropic glutamate receptor 5 (mGluR5, Kis = 16.4, 12.6, and 9.5 nM for the human, rat, and mouse receptors, respectively, in a radioligand binding assay). It is selective for mGluR5 over mGluR1, -2, -3, -4, -6, -7, and -8 (IC50s = >10 µM for all) and the histamine H1 and...
| Schlagworte: | 2-chloro-4-[2-[2,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]-1H-imidazol-4-yl]ethynyl]-pyridine |
| Anwendung: | mGluR5 inverse agonist |
| CAS | 871362-31-1 |
| MW: | 391.8 D |
ab 181,00 €
CTEP
Artikelnummer: TGM-T6457-100mg
Description: CTEP (RO 4956371) (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors. Target: GluR. Smiles: Cc1nc(C#Cc2ccnc(Cl)c2)c(C)n1-c1ccc(OC(F)(F)F)cc1. References: Lindemann L, et al. J...
| Schlagworte: | mGluR5 inhibitor , RO 4956371 |
| Anwendung: | mGluR5 inverse agonist |
| CAS | 871362-31-1 |
| MW: | 391.77 D |
ab 30,00 €
